Kind of a chicken and egg? Probably adjust the screws, do the synch and then readjust the screws. If you do a good eyeball synch you are likely to get em very close before they go on the bike. My method is to look through the intakes with a light source behind the carbs, adjsut the idle stop till there is the tineist sliver of light on the left carb adjust the synch screw till the right carb matches it, add back a turn or two of idle speed and install. This gets me within 1-3 psi on my gauges. It also confirms I have properly centered the butterflies after throttle shaft seal installation.