I've done this, can't tell you how it works long term, but it worked until I quit riding the bike. I found the thickest nitrile glove that I could find, cut a patch from that glove. I prepped the area with scotch brite then cleaned with isopropyl alcohol. I glued the patch on with Loctite Super Glue, Ultragel Control, comes in a blue and black little bottle, this glue is supposed to be flexible when cured. After the glue was cured I put another thin coat of glue around the edges of the patch. There's a lot of opinions on which side of the diaphragm to place the patch on, I don't remember which side I placed it on, I think it was the non-vacuum side. Also, this depends on the place and size of the hole.
Scott
