You can take the twisties to the Rock Store on Muholland hwy, 101Fwy to lost hills/las vergenes then to Muholland. I used to drive up on the weekends then end at PCH.
It is a good long drive but the break at the rock store helps...Great pancakes too.
Also there is Angeles Crest Hwy Off the 210/5 fwy north of Pasadena.
there are a ton of places north of the 210 or further west the 118.
I would love to head out there but my swingarm bushings are pretty loose, brakes are paper thin and my chain is questionable.
Have fun out there.